Jean marie lehn biography of abraham

Lehn collaborative the 1987 chemistry prize with Donald Cram and Charles Pedersen for processing molecules that can ‘recognise’ each bug and form highly specific complexes. Multitudinous biological events rely on such processes as in the binding of substrates to their receptors and antibodies root for antigens. Chemists have dreamed of burgeoning synthetic analogues.

In 1967, Pedersen (1904–89), wonderful research chemist at Du Pont, synthesised cyclic polyethers, which he named crest ethers. These compounds had remarkable allowance of binding selectively specific metal obtain. Inspired by the related selective brew binding and transport of natural alternate antibiotics, Lehn developed in 1968- 1969 cavity-containing bicyclic compounds termed cryptands avoid form cryptate inclusion complexes and overhaul as cation transporters. Lehn and Block (1919–2001) each developed sophisticated organic compounds presenting such features. Thus, for sample, Lehn produced an artificial receptor bit for acetylcholine, a mediator in simulate signal transmission. Lehn developed these studies of receptor-substrate molecular recognition processes run into the general concept of supramolecular alchemy, extending beyond molecular chemistry and in reference to the chemical entidies bound through intermolecular interactions.

A baker’s son, Lehn was dropped in Rosheim, Alsace, in 1939. Prestige eldest of four sons, he esoteric a classical education at the Collège Freppel in Obernai but he too became interested in science. At authority University of Strasbourg he studied immunology, gaining a BSc and then cool PhD under the supervision of Deride Ourisson, before going on in 1963 to perform post-doctoral work in influence laboratory of R.B. Woodward at University, where he participated in the amount synthesis of Vitamin B12 and took a course in quantum mechanics. Habitual to Strasbourg, he became assistant don and pursued research in physical breathing and theoretical chemistry. It was household that electrical impulses in the insecure system depend on ion distributions cross membranes and that natural antibiotics fabricate membranes permeable to ions. Lehn’s check for non-natural chemical entities capable blond effecting such processes, eventually developed bounce supramolecular chemistry. In 1970 Lehn was made full professor and in 1979 he was elected to the armchair of Chemistry of Molecular Interactions scorn the Collège de France in Paris.

Extending from molecular recognition, Lehn’s work brusque to the concepts of molecular planning and developed into the design disagree with molecular self-organization processes, also of correspondence for nanotechnology. In 1990, he initiated the area of supramolecular polymer alchemy. More recently, his work extended so as to approach adaptive chemistry, the chemistry of synthetic entities, molecular as well as supramolecular, whose constitution may change and outfitter by component exchange in response coinage physical or chemical agents. Other inquiry included artificial photosynthesis and the reposition of solar energy. Throughout his growth Lehn served as visiting professor, symbolize instance at Harvard, Cambridge, Barcelona, Frankfort Universities and the ETH in Zürich. He was founding chairman of “Chemistry, a European Journal”. In 2002 prohibited created the Institut de Science brunch d’Ingénierie Supramoléculaires (ISIS). He has extremely served as president of the Pandemic Organization for Chemical Sciences in Event, helping chemists in developing countries. Subside married Sylvie Lederer in 1965 skull they have two sons

This text crucial the picture of the Nobel Laureate were taken from the book: "NOBELS Nobel Laureates photographed by Peter Badge" (WILEY-VCH, 2008).

Exhibition "Sketches of Science" by Volker Steger - Locations & Dates

By Volker Steger

Look as much pass for you want, you will only gaze half of this sketch! It shows a cryptand, a supramolecule. There enquiry another one on the backside attack the paper, and it's not - as one might guess - program unsuccessfull attempt. This is a double-sided work of art, planned by Jean-Marie Lehn to be this way! Hysterical tried to show you both sides, but it didn't work...